Restart your computer.
  It's amazing how many onsite service calls are fixed by simply restarting the computer.  Many people (myself included) leave their computer running 24/7.  Eventually, something will get messed up in the system and the computer will start behaving very strangely.  The first thing you should always try is closing all applications and restarting the computer.

Verify your antivirus is working and run a system virus scan.
  If restarting your computer didn't fix the problem, try running a virus check.  Remember, you should see the antivirus software (Norton, Macafee, etc) icon in the taskbar on the lower right side of your screen (by the clock).  If it is missing, you may have a virus that actually disabled your antivirus program.  You will need to start the antivirus program and get any virus definition updates before running the scan.  A scan with out-of-date virus definitions is absolutely worthless.  Once you have verified your virus definitions are current, then run a scan.  See if it completes, and if it found viruses and was able to delete the virus and repair all files.  If the scan could not complete, then most likely your antivirus software has been corrupted (probably from a virus) and will need to be reinstalled. 

Stop and think for a minute about any programs or hardware you recently installed.
  Restarting didn't help, your virus scan came back with no viruses found, now think about what programs you may have recently installed.  Sometimes a program (especially an older piece of software) can conflict with another program.  Try uninstalling the last piece of software you recently installed and see if that corrects the problem.

Do a little reading.
  The next step would be to go to the website of the software company that you are having a problem with.  Almost every software company is going to have a help section where you can usually type in an error message and do a search for it.  Write down the error message exactly as it comes up on your computer and then do a search for it.  You will be surprised to find out that you are probably not the only person in the world to be having this problem with the software program.  Often the software company has already resolved this issue and has an article explaining how to fix the problem.  Many times this will resolve the problem in question...but not always.

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